Agoseris retrorsa appears to be most closely related to A. grandiflora. It superficially resembles A. parviflora and the two are sometimes confused. Agoseris retrorsa occurs primarily west of the Sierra Nevada; A. parviflora occurs primarily east of the same range. Cypsela characteristics will quickly separate them. Putative hybrids between A. retrorsa and A. grandiflora, A. hirsuta, and A. parviflora have been identified.